Discovering New Genes: Changing How We Detect and Treat Breast Cancer

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Scientists have uncovered four new genes linked to breast cancer, aiding in identifying women at higher risk for the disease. 

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The study, published in Nature Genetics, sheds light on cancer development mechanisms and potential new treatment avenues. 

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International researchers, led by University of Cambridge and Universite Laval, aimed to address limitations of existing genetic tests 

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Currently used tests focus on few genes (e.g., BRCA1, BRCA2), explaining only a fraction of genetic risk. 

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The study examined genetic changes across all genes in 26,000 breast cancer patients and 217,000 non-patients from Europe and Asia. 

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This is the largest study of its kind, facilitated by global collaboration and data from the UK Biobank. 

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Identifying these new genes enhances understanding of breast cancer's genetic risk, aiding better risk prediction and patient identification 

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The findings will impact breast cancer screening, risk reduction strategies, and medical management. 

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The goal is to integrate these findings into a comprehensive global risk prediction tool used by healthcare professionals. 

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